| (EJVP Vol5 No 3; page 115 Case 3)
Cytopathology Case
Lymph node fine needle aspirates from a dog
 ..
QUESTIONS:
A: Give a cytopathological dscription
B: What is the morphological diagnosis?
ANSWERS:
A The aspirate is composed of numerous mononuclear leucocytes and erythrocytes. At higher magnification a uniform cell population is characterised by a predominance of immature lymphoid cells (lymphoblasts). The tumour cells vary in size and exhibit scant dark blue staining cytoplasm. The nuclei contain loosely packed chromatin with numerous prominent and often irregularly formed nucleoli. Mitotic figures are rarely observed. In addition, few well mature lymphocytes and normal eryhtrocytes are intermingled between tumour cells.
B: Lymphosarcoma (malignant lymphoma)
Literature:
Duncan JR. The lymph nodes: in diagnostic cytology of the dog and cat. R Cowell and R Tyler Eds., American Veterinary Publications, Knc. 1989, 217-224
Fournel-Fleury G, MAgnol J-P, Guelfi J-F, Eds. Color Atlas of cancer cytology of the dog and cat. The lymph node. Conference Nationale des Veterinaires Specialises en Petits Animaux 82, avenue de Villiers - 75017 Paris 1994, 243-321
Thrall MA Cytology of lymphoid tissue. Comp. Cont Educ, 9: 104-112, 1987
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