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January 2017

Dog: Benign Prostatic hyperplasia

Signalment:

Juvenile male entire Beagle dog

Diagnosis:

Benign prostatic hyperplasia

Description:

Moderate, bilateral and symmetric enlargement of the entire prostate. The diagnosis was confirmed histologically as benign prostatic hyperplasia with acute prostatitis, necrosis and haemorrhage

Comments:
Benign prostatic hyperplasia (BPH) is a common age and testosterone dependent condition in dogs1. The dog is the only domestic animal that spontaneously develops prostatic hyperplasia with age. The young age of this dog is unusual for this condition but BPH can be seen dogs as young as 1 – 2 years old.
Enlargement of the prostate is hormone related, with acinar hyperplasia caused by androgen excess and fibromuscular hyperplasia caused by oestrogen excess, as in the case of Sertoli cell tumour induced BPH.

1Foster RA (2007) Male Reproductive system. In: McGavin MD, Zachary JF (eds) Pathologic basis of veterinary disease, 4th edn. Mosby Elsevier, St. Louis, p 301–391

Picture by: Dr James Baily Dipl ECVP, Charles River Laboratories, Edinburgh

Authored by: Dr James Baily Dipl ECVP, Charles River Laboratories, Edinburgh