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April 2011

Prarie Dog, kidney: severe, chronic, diffuse, nephritis with multiple cysts

Detailed information

History: prairie dog, 9 years

Diagnosis: kidney: severe, chronic, diffuse, fibrovesicular nephritis

Description: Both kidneys had multiple cysts with a maximum diameter of 4 cm. The capsule adhered diffus ely to the kidney’s surface which was rough and multifocally indented.

Comments: Clinically, the prairie dog clinically was apathic after hibernation with hypocalcaemia and hyperphosphataemia. At necropsy, severe cardiomegaly and arteriosclerosis were noted, in addition to the renal lesions.

Histologically: the kidneys had severe, chronic, diffuse, fibrovesicular and lymphoplasmacellular nephritis with multifocal glomerulosclerosis. The parathyroid glands were mildly hyperplastic. Mucous membranes and bones were unchanged

Picture by: Melanie Bothe, Department of Veterinary Pathology, Freie Universitaet Berlin, Germany

Author: Melanie Bothe, Department of Veterinary Pathology, Freie Universitaet Berlin, Germany