Pathology of Mouse Models for Human Disease
The goal of this 5-day workshop is to provide intense interactive sessions aimed at training the next generation of comparative pathologists and biomedical scientists who will be involved in the development and use of mouse models of human disease, while also providing a continuing education resource for those who have experience in the field. The workshop will focus on how mouse models of human diseases are being used in basic research and preclinical studies addressing the pathogenesis and/or efficacy of novel treatments.
Featured topics include:
• Selecting and developing preclinical mouse models, including genetically engineered resources and emerging genome-engineering technologies
• Mouse genetics, clinical pathology, embryology, background lesions, and histopathologic scoring
• Humanized, immunodeficient, and athymic mouse models
• Mouse models of cancer, hematopathology, rhabdomyosarcoma, respiratory disease, tuberculosis, and other infectious diseases
• Comparative pathology approaches used in pharmaceutical research and translational studies
• Advanced pathology methods, including multiplex immunohistochemistry and immunofluorescence, spatial technologies, and assay development
• Forward and reverse translation and New Approach Methodologies (NAMs)
• Practical approaches for selecting pathology endpoints, interpreting findings, and using pathology to address scientific questions.
The program also includes attendee presentations, interactive discussions, a tour of St. Jude, and in-person networking opportunities in Memphis, providing participants with opportunities to exchange ideas and build professional connections with faculty and fellow attendees.
For those unable to attend in person, virtual attendance will include the opportunity to interact via virtual chat, with most lectures also being available for 90 days as on-demand recordings.