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November 2008

Dog, Lung: Distemper virus infection (IHC)

Animal: Dog, 5 months old, male
History: The puppy was sent dead for diagnosis. The animal proceeded from a titter in which 3 more puppies died with unspecific symptoms. None of the animals were vaccinated. The mother did not have record of vaccinations.
Autopsy findings: the autopsy did not reveal great macroscopic lesions. The lungs were moderately firm an pale, the thymus was small.
Histology showed a diffuse enlargement of the interalveolar spaces due to the infiltration of mononuclear cells. Inmunohistochemistry of several organs showed strong immunostainig for distemper virus, mainly located in epithelial cells.
Diagnosis: Distemper virus infection